<bold>STAT6</bold>识别<bold>N4</bold>位点<bold>DNA</bold>的结构基础被揭示
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چکیده
منابع مشابه
A Parallel Pages Mining Approach: Combining URL Patterns and HTML Structures
刘奇,刘洋,孙茂松 (清华大学 计算机科学与技术系 智能技术与系统国家重点实验室,北京 100084) 摘要: 平行语料库是对机器翻译、跨语言信息检索等应用技术具有重要支撑作用的基础数据资源。虽然互 联网上的平行网页数量巨大且持续增长,但由于平行网站的异构性和复杂性,如何快速自动获取高质量的 平行网页进而构造平行语料库仍然是巨大的挑战。本文提出了一种 URL 模式与 HTML 结构相结合的平行网页 获取方法,首先利用 HTML结构实现平行网页的递归访问,其次使用 URL模式优化遍历平行网站的拓扑顺序, 从而实现高效准确的平行网页获取。在联合国与香港政府 1 两个平行网站上的实验表明,我们的方法相对传 统获取方法在获取时间上减少 50%以上,准确率提高 15%,并显著提高了机器翻译的质量(BLEU 值分别提 高 1.6 和 0.7 个百分点)。 关键词:平行网页获取;平行语料库;URL...
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Dll4是定位于人染色体15q14、基因编码长度为685 个氨基酸的单链跨膜蛋白。它在进化过程中高度保守, 人和鼠Dll4基因编码的蛋白具有87%的同源序列。Dll4 的胞外段含有与Notch受体结合必需的8个表皮生长因子 (epidermal growth factor, EGF)样重复序列、4个潜在的 糖基化位点和1个由45个氨基酸组成的保守DSL(Delta, Serrate, Lag2)结构域。 Dll4通过与相邻细胞膜上的Notch1或Notch4受体相 互结合,使Notch受体经过一系列蛋白酶裂解。这个过 程主要包含2个蛋白酶,即肿瘤坏死因子α转换酶(tumor necrosis factor α-converzyme, TACE)和早老素(presenilin) 或称为γ-分泌酶(γ-secretase),受体裂解后释放出活化 形式的胞内区域(notch intrace...
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ژورنال
عنوان ژورنال: SCIENTIA SINICA Vitae
سال: 2017
ISSN: 1674-7232
DOI: 10.1360/n052016-00324